Giving your trial the best chance of success

Background:

Sponsor company approached Paratus Clinical Research Woden to reconsider running their Phase 2 trial in the very rare condition, palmoplantar pustulosis (PPP) where site had previously declined due to unlikeliness to recruit.

Requirement:

Sponsor requested site to enrol 1 patient for the potentially successful injectable biologic.

Outcome:

•  Site enrolled 2 patients on the trial with the first patient enrolled being the first patient recruited globally.

• Outcome of the IP was hugely successful with PPP completely resolving for the patients.

• Very successful trial allowing patients relief from a high debilitating disease.

Background:

A small biotech company working with an Australian CRO looking for a site capable of long patient visits for their Ph2a Gout study.

Requirement:

The study required 9 PK samples across a 10 hour period with no overnight stay.

Outcome:

• Patients were onsite for 12 hours +
• Patients were constantly monitored by site staff throughout this period
• Patients were provided with office space to work from, lunch and drink vouchers for local cafes and entertainment to fill in their time

Background:

A Sponsor company working with an Australian CRO selected Paratus Clinical to be involved in a Hypercholesterolemia study for 20-80 year olds.

Requirement:

The initial study recruitment timeline was reduced and Paratus Clinical was requested to recruit more patients to ensure target was met.

Outcome:

• Huge patient interest from our recruitment advertising
• Paratus Clinical exceeded recruitment target
• Recruitment completed in 23 days, Sponsor timelines met

Background:

A global influenza vaccine company working with an Australian CRO looking for a Southern Hemisphere site for an Influenza study.

Requirement:

Study required 24 healthy volunteers over the age of 50 to be recruited 1 month prior to Australian flu season starting.

Outcome:

• Age range of participants and delay in study start up proved challenging for recruitment
• 3 Paratus sites recruited 80 participants in 7 weeks, this more than exceeded target
• Sponsor and CRO impressed with quality of patient data and study outcomes

Background:

A multinational pharmaceutical company needed to speed up development timelines for a new vaccine study.

Requirement:

The pharmaceutical company selected five sites in Australia(two from Paratus Clinical).Each site needed to recruit 12 women aged between 16-30 years of age.

Outcome:

• Paratus recruited 78% of Australian participants.
• Study recruitment closed on time.
• Speedy development of vaccine occurred.

Background:

An Australian biotech company had developed a new point-of-care diagnostic to detect influenza and needed access to patients with ‘influenza-like illnesses’ within72 hours of symptom onset.

Requirement:

Paratus worked closely with partner GP practices to set up referral pathways for eligible and interested patients, as well as setting up inside a GP practice to accommodate the study.

Outcome:

• Paratus recruited over 150 patients.
• The study was able to proceed with a statistically relevant number of patients.
• Development of the diagnostic tool was able to continue.

Background:

An Australian biotech developing a new migraine treatment had experienced difficulty in achieving successful patient recruitment.

Requirement:

The biotech company required fast recruitment after experiencing previous delays.

Outcome:

• Paratus delivered 120% of target in two months
• The biotech company was able to progress research to the next stage of development more rapidly than anticipated

Background:

A UK-based biotech company working with an Australian CRO required fast recruitment for a Phase II flu vaccine study.

Requirement:

Biotech company needed 2,200 healthy volunteers during the 2019 flu season.

Outcome:

• Paratus recruited 893 participants (more than double the initial target).
• Fast recruitment expectations were accomplished.
• Paratus Western Sydney clinic was the highest recruiting site.