The purpose of this study is to evaluate how safe and effective the investigational medicine is when taken over a longer period in adults with type 2 diabetes who are overweight or living with obesity.
You may be eligible if:
If eligible, you will take part in the study for up to 79 weeks, including screening, treatment, and a safety follow-up period. The study involves 17 clinic visits and 6 phone calls, with clinic visits occurring approximately once every 4 weeks. Most clinic visits require fasting and will take place during clinic business hours Monday to Friday, 8am–4pm.
During the study, you will receive a once-weekly subcutaneous (under the skin) self-injection of either the investigational medicine or a placebo. Participants are randomly assigned to treatment groups, and neither you nor the study team will know which treatment you are receiving.
Throughout the study, doctors and nurses will closely monitor your blood glucose levels, body weight, and overall health through regular check-ups and testing.
Study assessments may include physical examinations, vital signs, ECGs, blood tests, urine screening, weight and BMI measurements, functional assessments, pregnancy testing (if applicable), lifestyle support reviews, diabetes education, and professional nutrition counselling.
Before enrolling, the study doctor and clinical team will explain the study in detail, including findings from previous research, potential risks and benefits, and what participation involves.
Eligible participants will receive reimbursement for study-related time and travel.